Improper lengths of actin-thin filaments are associated with altered contractile activity and lethal myopathies.Leiomodin, a member of the tropomodulin family of proteins, is critical in thin filament assembly and maintenance; however, its role is Hardware under dispute.Using nuclear magnetic resonance data and molecular dynamics simulations, we ge
Exposure to antimuscarinic medications for treatment of overactive bladder and risk of lung cancer and colon cancer
Lukas Löfling, Anders Sundström, Helle Kieler, Shahram Bahmanyar, Marie Linder Centre for Pharmacoepidemiology, Department of Medicine, Karolinska Institute, Solna, Sweden Introduction: One out of six adults has symptoms of overactive bladder (OAB).Antimuscarinic medication is the main Hardware pharmacological group used in the treatment
A Comparative Study of Groundwater Recharge Mapping Using Analytical Hierarchy Process, Fuzzy- Analytical Hierarchy Process, and Frequency Ratio Models: A Case Study from Quetta Region, Pakistan
This study aimed to delineate groundwater recharge zones using a combination of analytical hierarchy process (AHP), fuzzy-AHP, and frequency ratio (FR) models.Additionally, it aimed to compare the effectiveness of these models in groundwater recharge potential zone mapping.To achieve these objectives, nine groundwater influencing factors were consi
Networks and learning: communities, practices and the metaphor of networks–a commentary
In issue 12(1), Jones (2004) in his article ‘Networks and learning: communities, practices and the metaphor of networks' sets out to address three inter-related sets of issues: … firstly that learning technology needs to take account of the wider debate about networks MIDI Controllers and secondly that research in this field ne
Nuclear Non-Proliferation and Disarmament in the Middle East
Nuclear non-proliferation and disarmament MANUKA HONEY 250+MGO in the Middle East are a sine qua non for security and stability in the region.Addressing them is of paramount importance and urgency if further breakouts are to be prevented.This has to be done in a comprehensive manner without prejudice or preference.The renewed JCPOA negotiations sho